血浆置换联合血液滤过治疗急性肝衰竭16例效果观察

Research on the effect of plasma exchange combined with hemofiltration in the treatment of 16 patients with acute liver failure

目的:探讨血浆置换(PE)联合血液滤过(HF)治疗各种原因引起的急性肝衰竭危重患者的效果。方法:将31例患者随机分为PE组15例与PE+HF组16例。观察并比较两组患者并发症情况、住院天数。结果:PE+HF组患者并发症发生率明显低于PE组(P<0.05),住院天数明显少于PE组(P<0.05)。结论:对于急性肝衰竭的危重患者,在其未并发肾衰竭前在行PE的基础上早期联合HF治疗可缩短其住院天数,减少并发症。

Objective： To investigate the effect of plasma exchange（PE） combined with hemofiltration（HF） in the treatment of acute liver failure caused by various factors.Methods： 31 patients were randomly divided into PE group（n=15） and PE ＋ HF group（n=16）.The complications and hospitalization days were observed and compared between the two groups.Results： The incidence of complications was significantly lower in the PE ＋ HF group than the PE group（P0.05）;the hospitalization days were evidently shorter in the PE ＋ HF group than the PE group（P0.05）.Conclusions： Plasma exchange（PE） combined with hemofiltration（HF） applied to the critically ill patients with acute liver failure can shorten the hospitalization days and reduce complications when acute renal failure does not occur.