摘要
以对羟基苯甲腈和叠氮钠为主要原料,采用点击化学法环加成合成一种质子导体5-(4-(3-二甲氧基甲基硅烷基丙氧基)苯基)-1H-四氮唑。通过单因素法考察了反应物配比、时间、温度对中间物5-(4-羟基苯基)-四氮唑收率的影响。最佳工艺条件为:n(对羟基苯甲腈):n(叠氮钠)=1:1.4,130℃,24h,50℃下酸化1.5h,中间产物收率达88%;中间产物在75℃下缩合获得目的产物5-(4-(3-二甲氧基甲基硅烷基丙氧基)苯基)-1H-四氮唑,收率可达78%。
Because of conjugate structure, azole nitrogen molecules can form a series of compounds, which have electrochemical stability. 5- （ 4- （ 3- （ Dimethoxy （methyl） silyl ） propoxy） phenyl ）-lH-tet- razole（B） was synthesized by click chemistry through cycloaddition and condensation reactions, that could be used for the preparation of new proton exchange membrane. In the synthesis of 5-（4 hydroxyphenol）-1H- tetrazole（A） experiments, the influences of same factors on product yield were investigated, such as the ratio of reactants, reaction time, acidification time, acidification tempera- ture. The opti 1 ： 1.4, 130~C tained. In the reaction conditions were , reaction time 24 h, acidified synthesis of 5-（4-（3-（dimeth found as follows： n（4-carbonitrile） ： n（sodium azide）= at 50 ℃for about 1.5 h, with the yield of 88% being at- oxy （methyl） silyl） propoxy） phenyl）-1H-tetrazole experi- ments, the yield was 78%. The synthesis process is simple, conditions are mild, with water as sol vent.
出处
《精细石油化工》
CAS
CSCD
北大核心
2011年第3期9-12,共4页
Speciality Petrochemicals
基金
河南省轨迹合作项目(编号:104300510009)
