期刊文献+

脑啡肽真的是“肽”极而否么?

Role of enkephalin in development of dementia of PTSD patients
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摘要 《普通精神病学档案》(Arch Gen Psychiatry)杂志在2010年6月刊登了一篇关于美国退伍老兵中创伤后应激障碍(PTSD)与患痴呆风险之间关系的前瞻性研究。研究显示,患有PTSD的退伍老兵患阿尔茨海默病及其他类型痴呆的风险将近其他退伍老兵的两倍。作者虽给出了这种相关性的解释,但我们发现脑啡肽可能也在这个过程中起作用。 A prospective study entitled “Posttraumatic stress disorder and risk of dementia among US veterans” was published in “Archives of General Psychiatry” on June, 2010. The research reported that older veterans who suffered from posttraumatic stress disorder (PTSD) were almost twice as likely to develop Alzheimer’s disease and other age-related dementias as veterans without PTSD. Though the reasons of the relationship between PTSD and dementia were given in the article, we found enkephalin may also play a part of role in it.
出处 《医学争鸣》 CAS 北大核心 2011年第3期28-30,共3页 Negative
关键词 创伤后应激障碍 脑啡肽 痴呆 阿尔茨海默病 posttraumatic stress disorder enkephalin dementia Alzheimer's disease
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参考文献14

  • 1Wimo A,Prince M.Alzheimer’’s Disease .The global economic impact of dementia. International World Alzheimer Report 2010 . 2010
  • 2Access economics.The dementia epidemic:Economic impact and positive solutions for Auslralia. http://www.alzheimers.org.au/ upload/EpidemicChapter3.pdf . 2003
  • 3Carson JA,Turner AJ.Beta-amyloid cataholism:roles for neprilysin (NEP) and other metallopeptidasesy. Journal of Neurochemistry . 2002
  • 4Yaffe K,Vittinghoff E,Lindquist K,et al.Posttraumatic stress disorder and risk of dementia among US veterans. Archives of General Psychiatry . 2010
  • 5Vasterling,J.J.,Proctor,S.P.,Amoroso,P.,Kane,R.,Heeren,T.,White,R.F.Neuropsychological outcomes of army personnel following deployment to the Iraq war. The Journal of The American Medical Association . 2006
  • 6KW Samuelson,TC Neylan,TJ Metzler,M Lenoci,J Rothlind,C Henn-Haase,G Choucroun,MW Weiner,CR Marmar.Neuropsychological functioning in posttraumatic stress disorder and alcohol abuse. Neuropsychology . 2006
  • 7Bremner J D,Randall P,Scott T M,et al.MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. American Journal of Psychiatry . 1995
  • 8Schuff N,Neylan T C,Lenoci M A,et al.Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder. Biological Psychology . 2001
  • 9Meilandt WJ,Yu GQ,Chin J, et al.Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer’’’’s disease. The Journal of Neuroscience . 2008
  • 10SISODIA S S,PRICE D L.Role of theβ-amyloid protein in Alzheimer’s disease. The FASEB Journal . 1995

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