肝硬化腹水合并低钠血症临床分析

Clinical Analysis of Liver Cirrhotic Ascites Patients with Hyponatremia

目的:探讨肝硬化腹水合并低钠血症的发病机制及低渗性脑病、肝肾综合征等并发症的发生率,并进一步探讨补充钠盐治疗的临床意义。方法:将86例肝硬化腹水患者依据血钠水平分为轻、中、重组,分析其并发症的发生率,并在综合治疗和利尿的基础上补充氯化钠,观察临床转归情况。结果:轻、中、重组发生低渗性脑病的比例分别为0%、12.5%、42.85%;发生肝肾综合征的比例分别为0%、8.33%、28.57%,经积极补充氯化钠后,腹水明显消退,低渗性脑病症状消失。结论:肝硬化腹水患者并发症的发生率与血钠水平呈负相关,适当补充钠盐是治疗的重要措施之一,有利于临床症状的好转。

Objective：To investigate the clinical significance of liver cirrhotic ascites patients with hyponatremia and the incidence rate of hypo-osmotic encephalopathy and hapato-renal syndrome.Methods：Blood sodium level of the patients with liver cirrotic ascites was determined.The patients were divided into mild,moderate and severe hyponatremia groups according to the blood sodium level and the incidence rate of complication was analysed.Results：The incidence rate of hypo-osmotic encephalopathy in mild,moderate and severe hyponatremia groups were 0%、12.5%、42.85% respectly.The incidence rate of hepato-renal syndrome were 0%、8.33%、28.57% respectly.As the level of blood sodium was elevated after the supplymentation of the sodium,the symptoms of encephalopathy erased or disappeared.Conclusions：The incidence of complication in the liver cirrhotic ascites patients with hyponatremia correlates negatively.