ICU内导管相关性感染细菌耐药性分析

ICU Catheter-related Infections of Bacterial Resistance

目的:ICU内导管相关性感染细菌分布与耐药情况。方法:2009-10～2010-10本院ICU院内感染患者35例的内导管病原菌的临床资料作回顾性分析。结果:所有患者共检出菌株97株,其中G-菌49株(50.52%),以非发酵菌最多。G+菌19株(19.59%),主要为肠球菌属和葡萄球菌。真菌29株(29.90%)。29株真菌中,对常用抗真菌药物如制霉菌素、两性霉素B均敏感,而对其他如5-FU、咪康唑、酮康唑、氟康唑均有不同程度的耐药。结论:ICU中的医院内导管感染率较高,G-菌则是感染的主要病原菌以为主。因此,应该对室内环境及导管严格控制,防范交叉感染的出现,减持无菌操作,治疗的同时配合内导管感染的防治。

Objective：ICU catheter-related infections and drug resistance of bacteria in the distribution.Methods：A retrospective study from October 2009 to October 2010 in our hospital ICU patients with nosocomial infections in 35 patients the clinical data of pathogens within the catheter.Results：All patients were 97 strains were detected,of which G-bacteria 49（50.52%）,most non-fermentative bacteria.G＋bacteria 19（19.59%）,mainly Enterococcus and Staphylococcus.Fungi,29 strains（29.90%）.29 strains of fungi,commonly used antifungal agents such as nystatin and amphotericin B were sensitive,while others such as 5-FU,miconazole,ketoconazole,fluconazole resistance in varying degrees.Conclusions：In the ICU higher infection rate of hospital catheters,G-bacteria were the main pathogens of infection based.Therefore,there should be strict control of indoor environment and the catheter to prevent the emergence of cross-infection,aseptic reduction,treatment,while prevention of infection with catheters.