晚期前列腺癌经尿道姑息性手术治疗观察

Effects observation of transurethral resection palliative surgery for advanced prostate cancer

目的:观察采取经尿道姑息性手术治疗晚期前列腺癌所致后尿路梗阻的临床疗效。方法:将本院收治的晚期前列腺癌所致后尿路梗阻的患者46例随机分为对照组与观察组各23例,对照组患者采取经尿道前列腺电汽化切除术治疗,观察组患者采取等离子体双极电切术治疗。术后观察对比两组的临床疗效。结果:经SPSS 18.0软件及卡方检验得出观察组较对照组在国际前列腺症状评分(IPSS)、马尔可夫随机场(MRF)、前列腺特异性抗原(PSA)以及残余尿量方面比较差异均有统计学意义(t值分别为2.253 6、3.344 3、2.448 3、2.989 9,P<0.05)。手术时间对照组为(61.87±27.62)min,观察组为(52.13±25.02)min,差异无统计学意义(t=1.0116,P>0.05)。出血量对照组为(93.71±37.45)ml,观察组为(50.53±24.57)ml(t=3.974 2,P<0.01);手术恢复时间对照组为(8.13±2.63)d,观察组为(6.06±1.84)d(t=2.569 0,P<0.05);并发症对照组14例,观察组2例(χ2=13.80,P<0.01),差异均具有统计学意义。结论:等离子体双极电切术具有术中出血少、易恢复以及不易产生术后并发症的显著优势,可有效缓解晚期前列腺癌患者的痛苦,为进一步内分泌治疗争取时间。

Objective：To observe the clinical effect of palliative transurethral surgery in treatment of advanced prostate cancer due to urinary tract obstruction.Methods：46 cases patients with advanced prostate cancer with urinary tract obstruction were randomized into control group and observation group in our hospital,23 cases in each.Control group patients were given transurethral vaporization resection for treatment and the observation group were given the plasma treatement.The postoperative clinical effect of two groups were compared.Results：The SPSS 18.0 software and Chi-square test observation group than in the control group reached the international prostate symptom score（IPSS）,Markov random field（MRF）,prostate specific antigen（PSA） and residual urine were with relative（t=2.253 6,3.344 3,2.448 3,2.989 9,respectivrly,all P0.05）,differences were significant.Observation group than in the control group,the control group in the operation time was（61.87±27.62） min,the observation group was（52.13±25.02） min,no significant difference;（t=1.011 6,P0.05） to compare the amount of bleeding in control group（93.71±37.45） ml The observation group was（50.53±24.57） ml（t=3.9742 P0.01）;Surgery recovery time in the control group was（8.13±2.63）d,the observation group was（6.06±1.84） days（t=2.569 0,P0.05）;The complications were group of 14 patients,2 patients in control group（χ2=13.80,P0.01）,differences were significant,with statistical significance.Conclusion：Bipolar patients plasma is with less bleeding,easy recovery,and difficult to produce a significant advantage of postoperative complications,can effectively alleviate the suffering of patients with advanced prostate cancer,gain time for further endocrine therapy.