下肢骨折围术期抗凝治疗对下肢深静脉血栓形成的影响

Lower limb fractures perioperative anticoagulant therapy in the lower extremities,the influence of deep venous thrombosis

目的:探讨下肢骨折围术期抗凝治疗对下肢深静脉血栓形成的影响。方法:分析2008～2011年152例接受下肢骨折手术、围术期应用低分子肝素钙或口服利伐沙班片的患者(A组)的临床资料,统计血栓发生率,同2008年152例前下肢骨折围术期未予抗凝药物干预的患者(B组)血栓发生情况进行对比。结果:A组8例(5.26%)发生深静脉血栓,B组38例(25.00%)发生深静脉血栓,两组比较,差异有统计学意义(P<0.05);且两组均未发生明显大出血。结论:围术期积极抗凝治疗,可大大降低下肢深静脉血栓形成的发生率。

Objective：To observe lower limb fractures perioperative anticoagulant therapy of lower limb vein thrombosis influence.Methods：Since 2008 to 2011,152 patients accepted lower limb fractures surgery,perioperative used low molecular heparin calcium or Rivaroxaban tablets slice of patients（group A）,statistical thrombosis incidence of 2008,152 Patients with lower limb fractures perioperative instabilities anticoagulant utilized intervention of patients（group B）thrombosis occured by comparing.Results：A group of eight cases（5.26%） had deep vein thrombosis,group B 38 cases（25.00%） had deep vein thrombosis,two groups,the difference was statistically significant（P0.05）.And two groups were not pronounced hemorrhage.Conclusion：The perioperative active anticoagulant therapy can greatly reduce varicose veins thrombosis incidence.