冠脉狭窄程度与血脂脂蛋白及中医证型关系

Relationship between severity of coronary stenosis and blood lipid and lipoprotein and syndrome types in TCM

对 1 0 9例确诊为冠心病的患者行冠状动脉造影术 ,判断冠脉狭窄程度 ,进行中医辨证分型 ,并检测血脂、脂蛋白的变化。结果表明 ,冠脉重度狭窄者甘油三酯均高于冠脉正常和轻度狭窄组 ,HDL -C、HDL2 -C、LDL -C/HDL -C、TC-HDL-C/HDL-C在各狭窄组均与正常组有显著性差异。在冠脉正常组 ,气证多于血证 ,重度狭窄组则相反。 HDL2 -C在各组间气证均高于血证 ,TC-HDL-C/HDL-C则相反。提示 :血瘀是导致冠脉狭窄的病理基础 ,HDL2 -C。

CHD patients were analyzed on the relationship between the degree of stenotic lesions in coronary artery and LP of blood-lipid and syndrom differentiation typing.The results showed that the TG in severe stenotic lesions patients in coronary artery was significantly higher than that in slight stenotic lesions and normal ones in coronary artery,but there was a striking difference between the patients of stenotic lesions and normal in coronary artery in the HDL C,HDL 2 C,LDL C/HDL C,TC HDL C/HDL C.The qi syndrome was outnumber the xue syndrome in the normal coronary artery patients,which was contrary to severe stenotic lesions patients.The HDL 2 C in qi syndrome was higher than that in xue syndrome,contrary to the TC HDL C/HDL C.The results suggested that the pathologic basis of causing stenotic lesions in coronary artery was blood stasis,the HDL 2 C,TC HDL C/HDL C might be taken as a good criterion for the study of CHD in syndrom dirrerentiation typing.