彩色多普勒超声在11～14周胎儿筛查中应用价值探讨

目的探讨彩色多普勒超声在11～14周胎儿筛查中的临床应用价值。方法选取自2009年1月～2011年1月2068例孕周在11～14周的孕妇(胎头臀长度均为45～84mm),应用彩色多普勒超声对其进行胎儿筛查,记录相关数据,进行统计学分析。结果筛查结果中,胎儿总数2068例,单胎1981例,双胎87例,疑似异常胎儿24例,其中7例颈项透明层(NT)≥3.0mm;9例NT≥3.0mm合并其他异常;7例单纯解剖结构异常,包括多发畸形1例,脐带膨出1例,胎盘部分性葡萄胎1例,脉络丛囊肿1例,中枢神经系统畸形3例(露脑畸形2例和无脑儿1例);1例静脉导管血流频谱异常。结论彩色多普勒超声在11～14周胎儿筛查中具有重要的临床意义,能够提供重要的遗传学信息,及早发现严重的胎儿解剖结构异常,为临床诊疗提供依据。

Objective To evaluate color Doppler ultrasound in 11-14 weeks,the clinical value of fetal screening.Methods In our hospital from January 2009 to January 2011,2068 cases of 11-14 weeks gestational age in pregnant women（fetal head rump length are 45-84mm）,color Doppler ultrasound screening of their fetal record relevant data were statistically analyzed.Results The screening results,the total number of 2068 cases of fetus,fetal 1,981 cases of single,twin 87 cases,24 cases of suspected fetal abnormalities,including 7 cases of neck and transparent layer（NT） 3.0mm;9 cases NT 3.0mm combined with other anomalies;7 cases of simple anatomical abnormalities,including multiple malformations in 1 case,1 case out of the umbilical cord swelling,partial mole placenta,1 case of choroid plexus cysts in 1 case,the central nervous system malformation in 3 cases（exposed brain Deformity in 2 cases and no brain child in 1）;1 case of abnormal venous catheter blood flow spectrum.Conclusion Color Doppler ultrasound screening at 11-14 weeks the fetus has important clinical significance,can provide important genetic information,early detection of severe fetal anatomical abnormalities,provide the basis for clinical treatment.