孕妇血小板抗体与新生儿血小板减少的相关性研究

目的探讨孕妇的血小板抗体与新生儿出现血小板减少是否有关联性,从而为临床治疗提供理论依据。方法随机选取收治的妊娠合并血小板减少的孕妇70例作为观察组,以同期入院的90例血小板正常的孕妇作为对照组,比较两组新生儿出现血小板减少的发生率,并分析非特异性抗体和特异性抗体与新生儿血小板减少发生率的关系。结果观察组孕妇分娩的新生儿其血小板减少发生率要明显高于对照组,其差异具有统计学意义(P<0.05);抗血小板非特异性抗体与新生儿血小板减少发生率关系更为密切,具有统计学意义(P<0.05)。结论孕妇血小板减少会引起新生儿的血小板减少,其主要原因是母体非特异性、特异性血小板抗体阳性,引起新生儿发生血小板减少症。临床医生需在妊娠分娩的不同阶段采取不同的治疗方法降低新生儿血小板减少的发生率。

Objective To explore the pregnant women and babies acquiring platelet antibody thrombocytopenia and whether there is a relevance,provides the theory basis for clinical treatment.Methods Randomly selected from the pregnancy with thrombocytopenia 70 cases of pregnant women as the observation group,and the same period of 90 cases of platelet normal hospital of pregnant women as control group,compared between the two groups in the incidence of newborn thrombocytopenia.And analyze the specific antibodies and specific antibodies and neonatal platelets to reduce the incidence of relationship.Results The observation group of the pregnant women delivery newborn thrombocytopenia rate was higher than those in the control group,the differences are statistically significant（P 0.05）;Antiplatelet nonspecific antibody and neonatal platelets are more closely related to reduce rates,a statistically significant（P 0.05）.Conclusion Pregnant women thrombocytopenia can cause of the newborn thrombocytopenia,the main reason is that maternal nonspecific,specific platelet antibody positive,and cause newborns occur thrombocytopenia.Clinical doctors should be in the different stages of pregnancy delivery to take different treatment reduce infant happen the incidence of thrombocytopenia.