抗菌消炎胶囊质量标准研究

Study on Quality Standard of Kangjun Xiaoyan Capsule

目的:建立抗菌消炎胶囊质量标准。方法:采用薄层色谱法对处方中的百部、大黄进行定性鉴别;采用高效液相色谱法测定该制剂中黄芩苷含量。结果:TLC鉴别分离度好,阴性对照无干扰。黄芩苷与样品中其他组分分离效果较好,Y=43 887 599.5X-4 893.8,线性范围0.01～0.16 g.L-1(r=0.999 9),平均回收率为98.56%,RSD为1.01%(n=6)。结论:建立的质量标准,简便易行,可用于抗菌消炎胶囊的质量控制。

Objective：To establish the quality standard of Kangjun Xiaoyan Capsule.Method：The identification of Radix stemonae and Radix et rhizome rhei were carried out by TLC.The content of baicalin was determined by HPLC.Result： The TLC spots were clear and separated well without interference of negative sample.The calibration curve of baicalin was linear in the range of 0.01-0.16 g·L-1,Y=43 887 599.5X-4 893.8（r=0.999 9）.The average recovery was 98.56% with RSD 1.01%（n=6）.Condusion： The method is simple,rapid and accurate.It can be used for the quality control of Kangjun Xiaoyan Capsule.