苦皮藤根皮的化学成分

Chemical Constituents of Root Barks of Celastrus angulatus

目的:研究苦皮藤根皮醇提物的化学成分。方法:采用硅胶柱色谱和高效液相分离纯化,通过NMR鉴定化合物的结构。结果:分离并鉴定了11个化合物,分别为celahin B(1),celastrine A(2),celahin D(3),苦皮素E(4),苦皮素A(5),celangulatin C(6),苦皮藤素XIX(7),苦皮素P(8),苦皮素H(9),苦皮藤素III(10),苦皮素J(11)。结论:化合物1～3为首次从苦皮藤中分离得到。

Objective：To study the chemical constituents from the alcohol extract of root bark of Celastrus angulatus.Method： The compounds,whose structures were confirmed by NMR spectra,were separated and purified by silica gel and preparative HPLC.Result： The structures of eleven compounds were conformed,they were celahin B（1）,celastrine A（2）,celahin D（3）,angulatin E（4）,angulatin A（5）,celangulatin C（6）,celangulin XIX（7）,angulatin P（8）,angulatin H（9）,celangulin III（10）,and angulatin J（11）.Conclusion： Compound 1-3 were first found in C.angulatus.