总有机碳分析仪测定药包材易氧化物方法的探讨

Study on measuring method of medicinal media materials by total organic carbon meter

目的:探讨利用总有机碳分析仪检测药品包装材料中易氧化物方法的可行性。方法:选择蔗糖对照品作为标准易氧化物,根据不同浓度的蔗糖溶液消耗相应体积的硫代硫酸钠滴定液,建立标准曲线,从而制定一个适宜的易氧化物限度。结果:3批样品按化学滴定法和总有机碳检测法检查,均低于规定的限度。结论:总有机碳分析仪可以用于药品包装材料中易氧化物的检测,具备准确、方便的优点。

Objective：The experiment was designed to discuss whether it is available to measure medicinal media materials by method of organic carbon meter.Methods：Sucrose was used as the oxidative standard.According to the ratio of the sucrose solution volume to the sodium thiosulphate solution volume,the standard working curve was set up.Results：The three series of samples were assessed by the traditional chemical method and the total organic carbon method and their concentrations were lower than the limit by rule.Conclusion：The total organic carbon meter could be used in assessment of oxidative mass in the medicinal media materials,and this method is accurate and convenient.