超声心动图评价干细胞移植对急性心梗患者左室重构的抑制作用

Evaluation of the Impact on Left Ventricle Remodeling in Acute Myocardial Infarction Patients with Bone Marrow Cells Transplantation by Echocardiography

目的:应用超声心动图评价经皮冠状动脉介入治疗(PC I)联合应用自体骨髓干细胞移植对急性心梗患者左室形态、结构和功能的影响。材料与方法:对照组与试验组分别于术前、术后1月、6月测量左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、射血分数(EF)和室壁运动记分指数(WMSI)。结果:试验组术后1月WMSI、6月时EF值、LVEDV和LVESV与对照组差异均有显著性意义。结论:联合应用自体骨髓干细胞移植,可更加有效阻止左室重构的进程。

Purpose：To evaluate impact on left ventricle remodeling in patients with acute myocardial infarction（AMI） using bone marrow cells transplantation by echocardiography.Materials and Methods：Twenty-four patients received percutaneous coronary intervention（PCI） with bone marrow cells transplantation were examined by echocardiography before operation and after one month and six month operation,as control group with traditional PCI.Left ventricular end-diastolic volume（LVEDV）,left ventricular end-systolic volume（LVESV）,ejection fraction（EF） and wall motion index（WMSI）,were measured in each patients.Results：Compared with control group,WMSI was significantly higher in every echo exam post-operatively.EF,LVEDV and LVESV was lower after six month in distal protection devices group.Conclusion：Left ventricle remodeling was prevented effectively by using bone marrow cells transplantation.