四氢叶酸模型的基团转移反应合成β—咔巴啉生物碱衍生物

The Group Transfer Reactions of Tetrahydrofolic Model, The Synthesis of β-Carboline Nkaloids

中药苦木中生物碱β—咔巴啉衍生物是一种重要生物碱。通过四氢叶酸模型化合物碘化1.2—二甲基—3—对甲氧苯磺酰基咪唑啉的基团转移反应,合成了此类生物碱衍生物——胡秃子碱衍生物。

β-acrboline alkaloids is a kind of important alkacoids in picrasma quassioides.The β-Carboline alkaloids-I-nitro-eleagnine had been synthesize by the group trausferreaction of tetrahydrofolic model compound:Substituted imida20linium salt,1. 2 -dimethyl -3 -1p-methoxybenzenesulfonyl J-imida20linium iodide.