摘要
成纤维细胞是瘢痕形成的效应细胞,瘢痕疙瘩和肥厚性瘢痕成纤维细胞存在着广泛的异质性。成纤维细胞胶原合成增加、降解减少导致病理性瘢痕中胶原过度积聚。成纤维细胞的增殖异常是病理性瘢痕过度增生和持续存在的主要原因。成纤维细胞对细胞因子等因素反应性有明显异常。肥厚性瘢痕的收缩性和成纤维细胞的异质性有直接关系。
出处
《国外医学(皮肤性病学分册)》
1999年第6期336-339,共4页
Foreign Medical Sciences(Section of Dermatology and Venereology)
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