2010年北京市顺义区麻疹疫苗强化免疫预防接种异常反应分析

Analysis on Results of Adverse Events Following SIAs in Shunyi District

目的评价2010年北京市顺义区麻疹疫苗强化免疫活动中异常反应发生情况,为今后此类工作的开展提供科学依据。方法对2010年顺义区麻疹疫苗强化免疫活动中出现的预防接种异常反应(AEFI)病例进行统计分析。结果顺义区共报告AEFI病例55例,报告发生率65.3/10万,其中,一般反应和异常反应分别为20和12例。异常反应中主要为过敏性皮疹,占91.7%。<1岁组AEFI发生率最高,98.2%的AEFI为接种后2天内发生。结论麻疹疫苗安全性较高。在今后工作中,应保持较高的AEFI报告灵敏度,健全鉴定赔偿机制,提高专业人员处置能力。建议在开展大规模接种前做好社会宣传和告知,提高公众对预防接种的认识。

[Objective]To evaluate the adverse events following the measles supplementary immunization activities（SIAs）,and provide scientific evidence for safety for SIAs.[Methods]The cases with adverse events following immunization（AEFI） were analyzed statistically in SIAs of Shunyi District in 2010.[Results]A total of 55 cases of AEFI were reported in Shunyi District,with the reported incidence of 65.3/100 000.Among which,20 cases and 12 cases were the common vaccine reaction and adverse reaction,respectively.91.7% of adverse reactions were allergic rash.Under 1-year-old group had the highest incidence,98.2% cases were reported in 2 days after immunization.[Conclusion]The measles vaccine is safe.The report of AEFI should be maintained a high sensitivity.It is necessary to improve the identification and the compensation mechanism to improve the ability of professionals to deal with AEFI.It is suggested to enhance social propaganda before extensive vaccination so as to increase public awareness of vaccination.