北京市金融街地区甲流流行后健康人群抗体水平的调查

A Survey on Levels of Antibody against Influenza A(H1N1) Virus after Outbreak among Healthy Population in Financial Street Area of Beijing

目的了解甲型H1N1流行性感冒(甲流)大流行后北京市金融街地区健康人群甲流血清抗体水平,为今后的流感防控提供有益的参考。方法随机选择北京市金融街地区健康人群250人作为调查对象,采用血凝抑制试验测定甲流抗体,并进行相关问卷调查和流行病学分析。结果 250名健康人群甲流抗体阳性率为25.6%(64/250),男女性别间抗体阳性率差异无统计学意义(P>0.05),接种甲流疫苗组与未接种疫苗组阳性率差异有统计学意义(P<0.05),有流感样症状者与未出现流感样症状者抗体阳性率差异有统计学意义(P<0.05),3-5岁和6-15岁年龄组人群阳性率最高,分别为50%和54%。结论北京市金融街地区健康人群中25.6%的人已具有甲流抗体,已形成有效的免疫屏障。

[Objective]To learn the serum antibody levels to influenza A（H1N1） virus after pandemic outbreak among healthy population in financial street area of Beijing,provide a reference for future prevention and control of influenza.[Methods]250 healthy people in financial street area of Beijing were randomly chosen as the investigation object,the hemagglutination inhibition test was applied to test the antibody against the influenza A（H1N1） virus,and related questionnaire and epidemiological analysis were conducted.[Results]The positive rate of influenza A（H1N1） antibody of 250 healthy people was 25.6%（64/250）,and there was no significant difference in positive rate between males and females（P0.05）.The difference in positive rate between the vaccination group and the non-vaccinated group was significant（P0.05）.There was significant difference in positive rate between people with and without influenza-like symptoms（P0.05）.The positive rate of 3-5 years age group and 6-15 years age group was the highest,which was 50% and 54% respectively.[Conclusion]25.6% of healthy people in financial street area of Beijing have influenza A（H1N1） antibody,and effective immune barrier has been formed.