瑞舒伐他汀钙对脑梗死患者血脂、超敏C-反应蛋白水平的影响

Effect of Rosuvastatin on lipoprotein and high sensitivity C-reactive protein in cerebral infarction patients

目的观察瑞舒伐他汀钙干预后对脑梗死患者血脂和C-反应蛋白水平的影响。方法选取96例脑梗死合并高脂血症的患者,随机分为观察组49例和对照组47例。分别予以瑞舒伐他汀钙、阿托伐他汀钙治疗,用药6周后检测血清脂蛋白、超敏C反应蛋白(hs-CRP)水平。结果观察组较对照组血清低密度脂蛋白、超敏C反应蛋白(hs-CRP)显著降低(P<0.05),从而降低脑血管疾病的发生。结论瑞舒伐他汀钙可降低脑梗死患者的血脂及hs-CRP水平,对预防脑血管疾病具有较好的作用。

Objective To observe the effects of Rosuvastatin on lipoprotein and C-reactive protein.Methods Ninety-six cases of patients with cerebral infarction merger hyperlipidemia were selected.All of them were randomly divided into observation（49 cases） and control（47 cases） groups.They were treated by Rosuvastatin and Atorvastatin respectively.Six weeks after drug treatment,the levels of lipoprotein and C-reactive protein were determined.Results The level of LDL-C and C-reactive protein induced by the observation group was lower than that of the control group.It indicated that Rosuvastatin may reduce risk factors of cardial-cerebral disease.Conclusion Rosuvastatin has a good effect on reducing the level of lipoprotein and C-reactive protein.And it could also prevent the occurrence of cerebrovascular disease.