利凡诺联合复方米非司酮在中期妊娠引产中的应用

Clinical effects of combined application of Rivanol and Compound Mifepristone in the induced abortion during middle pregnancy

目的探讨利凡诺联合复方米非司酮终止中期妊娠的临床效果。方法选择100例中期妊娠健康妇女,随机分为试验组和对照组,每组50例。试验组行利凡诺和复方米非司酮联合治疗;对照组单纯行利凡诺治疗。结果 72 h内引产成功率试验组为100%,对照组为96%(P<0.05);胎儿及胎盘娩出时间分别为(12.14±4.89)h和(6.98±2.46)h,两组差异有统计学意义(P<0.05);胎盘、胎膜残留及2 h出血量例数试验组少于对照组(P<0.05)。结论利凡诺联合复方米非司酮终止中期妊娠效果优于单纯应用利凡诺。

Objective To explore the clinical effects of combined application of Rivanol and Compound Mifepristone in the induced abortion during middle pregnancy.Methods One hundred healthy women of medium-term termination of pregnancy were equally randomly divided into two groups： observation group and control group.Observation group was given oral Compound Mifepristone and injected Rivanol into amniotic;Control group only used Rivanol.Results The achievement ratio of induced abortion in 72 hours was 100% in observation group and 96% in control group（P0.05）.The efflux time of the fetal and its affiliated were（12.14±4.89） h and（6.98±2.46） h respectively.There were great statistical significance between two groups（P0.05）.The cases of afterbirth residual and bleeding 2 h after laboring were less in observation group than that in control group（P0.05）.Conclusion The effect of combined application of Rivanol and Compound Mifepristone was better than that of single peritoneal injection of Rivanol in the induced abortion during middle pregnancy.