摘要
目的:为合理使用基本药物提供参考。方法:采用回顾性研究方法,对淮北市2010年1-12月收集的2 503例基本药物不良反应(ADR)报告进行分类、汇总及分析评价。结果:涉及ADR的基本药物中抗感染药物居首位,给药途径以静脉滴注为主,累及系统/器官主要为皮肤及其附件损害,涉及国家ADR通报品种40种。结论:应合理使用抗感染药物,慎重选择静脉滴注给药方式。中药注射剂的ADR不容忽视,进一步加强基本药物重点监测,确保公众用药安全。
OBJECTIVE: To provide reference for safe application of essential drugs. METHODS: By retrospective study, 2 503 essential drugs-induced ADR reports collected form our city during Jun.--Dec. 2010 were classified, summarized, analyzed and evaluated. RESULTS: Anti-infective drugs were at the first place, the main route of administration was intravenous drip, and the systems or organs involved in ADRs were lesion of skin and its appendants. 40 kinds of national reported ADR-inducing drugs were involved. CONCLUSION: Anti-infective drugs should be used rationally, and intravenous drip treatment should be selected carefully. TCM injection-induced ADR should not be overlooked, and essential drugs monitoring should be further strengthened to ensure the safe drug use.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第28期2635-2638,共4页
China Pharmacy
关键词
基本药物
不良反应
分析
Essential drugs
Adverse drug reaction
Analysis