基于Web of Science的药物基因组学文献计量分析

Bibliometric analysis of pharmacogenomic literature based on Web of Science

目的:确定药物基因组学文献分布特点和主要研究方向,为今后研究药物基因组学相关课题提供依据。方法:运用文献计量学的方法对Web of Science数据库收录的药物基因组学相关文献进行分析。结果:统计范围内共有8 037篇文献,近年来文献数量增长迅速,确定了以《Pharmacogenomics》为主的10种药物基因组学核心期刊,以Mcleod HL为首的10位多产作者及被引频次居前10位的文献。近几年来中国在药物基因组学研究取得了巨大的进步,但是仍落后于世界先进国家。结论:药物基因组学研究领域越来越受重视,相应的科研产出量将持续增加,我国研究者应该加强国际合作与研究水平。

Objective：To investigate the distribution characteristics and research direction of pharmacogenomics,and to provide a basis for further scientific research.Methods：Articles were searched from Web of Science and analyzed by bibliometrics.Results：A total of 8037 references of pharmacogenomics were recorded.The total number has increased quickly during the recent years.The top 10 core journals were found such as Pharmacogenomics,and Mcleod HL is the prolific writer.Top 10 papers of pharmacogenomics in terms of cited frequency were also listed.A great progress has achieved in pharmacogenomic research during the past years in China,but is still lagging behind developed countries.Conclusion：The pharmacogenomics has attracted more and more attention.More studies on pharmacogenomics are expected in the future,and the level of investment and research should be improved in China.