期刊文献+

胰岛移植的研究进展 被引量:4

下载PDF
导出
摘要 绝大多数1型糖尿病是由于自身免疫破坏胰岛B细胞,导致胰岛素分泌不足,进而造成体内糖代谢紊乱,并引发全身多器官功能损害。目前1型糖尿病的治疗主要依靠外源性胰岛素注射,但这种方法不能有效控制血糖使之稳定,也不能避免远期并发症,而且低血糖昏厥发生率较高。
出处 《器官移植》 CAS 2011年第4期233-236,共4页 Organ Transplantation
  • 相关文献

参考文献2

二级参考文献25

  • 1王维娜,邵广州,杨海东,薛勤东.胎儿胰腺及胸腺联合移植治疗Ⅰ型糖尿病的疗效观察[J].中华器官移植杂志,1994,15(4):168-170. 被引量:4
  • 2陈灏珠.内科学.第4版[M].北京:人民卫生出版社,1996.792.
  • 3Akima S, Hawthorne WJ, Favaloro E, et al. Tirofiban and activated protein C synergistically inhibit the Instant Blood Mediated Inflammatory Reaction (IBMIR) from allogeneic islet cells exposure to human blood [J]. Am J Transplant, 2009, 9 (7): 1533-1540.
  • 4Bennet W, Groth CG, Larsson R, et al. Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes[J]. Ups J Med Sci, 2000, 105 (2): 125-133.
  • 5Goto M, Tjemberg J, Dufrane D, et al. Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation [J]. Xenotransplantation, 2008, 15 (4) : 225-234.
  • 6Cabric S, Sanchez J, Lundgren T, et al. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation [J]. Diabetes, 2007, 56 (8): 2008-2015.
  • 7Ozmen L, Ekdahl KN, Elgue G, et al. Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation [J]. Diabetes, 2002, 51 (6): 1779-1784.
  • 8Prydz H, Camerer E, Rottingen JA, et al. Cellular consequences of the initiation of blood coagulation [J]. Thromb Haemost, 1999, 82 (2): 183-192.
  • 9Prydz H. A new paradigm for blood coagulation research [J]. Thromb Haemost, 2000, 83 (4): 520, 522.
  • 10Pendurthi UR, Rao LV. Factor Vlla/tissue factor-induced signaling: a link between clotting and disease [J]. Vitam Horm, 2002, 64: 323-355.

共引文献7

同被引文献47

引证文献4

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部