1535例育龄妇女巨细胞病毒IgG和IgM抗体检测分析

Study on serum levels of CMV-IgG and CMV-IgM in 1 535 women at childbearing age

目的通过对育龄妇女人巨细胞病毒（CMV）IgG和IgM水平的调查,了解育龄妇女对巨细胞病毒免疫力和近期感染状况。方法采用酶联免疫吸附试验（ELISA）方法对1 535例育龄妇女进行血清CMV-IgG和CMV-IgM水平检测。结果 1 535例育龄妇女CMV-IgG阳性率为47.82%,其中20-29岁组和30-40岁组阳性率分别为50.51%和42.99%,两组比较有显著差异（P〈0.05）;CMV-IgM阳性率为10.75%,其中20-29岁组和30-40岁组阳性率分别为11.05%和10.20%,两组比较无显著差异（P〉0.05）。结论约有一半的育龄妇女对CMV有免疫力,育龄妇女中CMV近期感染率呈上升趋势。

Objective To study the infection and immunity to human cytomegalovirus（CMV） in women at childbearing age.Methods The serum levels of CMV-IgG and CMV-IgM in 1535 women at childbearing age were determined by enzyme-linked immunosorbent assay（ELISA）.Results Their positive rate of CMV-IgG was 47.82%,and positive rates in 20～29 age group and 30~40 age group were 50.51% and 42.99% respectively,their difference was statistically significant（P0.05）.The positive rate of CMV-IgM was 10.75%,and the positive rates in 20～29 age group and 30~40 age group were 11.05 % and 10.20% respectively,and their difference was not significant（P0.05）.Conclusion About half of the women at childbearing age have immunity to CMV and the infection rate of CMVshows an increasing tendency in women at childbearing age.