摘要
目的探讨急性脑血管病患者血清肌钙蛋白T(cTnT)、总三碘甲腺原氨酸(T3)的水平及临床价值。方法选取经颅脑CT确诊的急性脑血管病患者80例,其中脑出血38例,脑梗死42例。并选60例健康体检者作为对照组。观察记录各组对象入院时、入院后第3天和第7天血清cTnT和T3水平。结果与对照组比较,入院时急性脑血管病患者cTnT显著上升,T3水平显著降低,差异有显著性(P<0.01),但随着病情缓解cTnT与T3均有所变化。脑出血与脑梗死cTnT水平比较,差异无显著性,但T3水平脑出血组降低更明显,差异有显著性(P<0.05)。神经功能受损程度越严重,cTn-T、T3含量越高。结论急性脑血管病患者存在血cTnT、T3异常,并与急性脑血管病病情严重程度有关,检测cTnT、T3对临床辅助判断急性脑血管病病情和预后具有重要指导意义。
Objective To investigate the clinical significance of serum cardiac troponin T(cTnT) and triiodothyronine(T3) in patients with acute cerebrovascular disease.Methods Brain CT confirmed eighty cases of acute cerebrovascular disease(cerebral hemorrhage 38,cerebral ischemia 42) and 60 healthy subjects were included in this study.Serum cTnT and T3 levels were detected on the day of admission and on day 3 and day 7 after admission.Results Compared with control group,serum cTnT level increased significantly,T3 level decreased significantly on the day of admission in patients with acute cerebrovascular disease(P0.01),but both cTnT and T3 changed after remission of the disease.There was no significant difference in cTnT level between cerebral hemorrhage and cerebral ischemia patients,but T3 level significantly decreased in cerebral hemorrhage patients when compared with cerebral ischemia patients(P0.05).The levels of cTnT and T3 were positively related to the severity of neurological damage.Conclusion Both serum cTnT and T3 levels change in patients with acute cerebrovascular disease,and the severity of the disease is related to the abnormality.The detection of cTnT and T3 may helpful for determining the condition and prognosis of the patients with acute cerebrovascular disease.
出处
《临床和实验医学杂志》
2011年第13期1005-1007,共3页
Journal of Clinical and Experimental Medicine