粘鱼须威灵仙棉团铁线莲对非特异性免疫的影响比较

Comparative Study Between Effects of Smilax sieboldii Miq.,Clematis chinensis Osbeck. and C. hexapetala Pall. on Non-specific Immunity

目的比较粘鱼须、威灵仙、棉团铁线莲对非特异性免疫的影响,为粘鱼须能否作为威灵仙入药提供科学依据。方法选择小鼠碳粒廓清法和腹腔巨噬细胞吞噬鸡红细胞法进行比较3种药物。结果粘鱼须、威灵仙、棉团铁线莲均能抑制小鼠单核巨噬细胞和腹腔巨噬细胞的吞噬作用,降低机体非特异性免疫反应能力。结论粘鱼须可以作为祛风湿药威灵仙使用。

Objective To compare the effects of Smilax sieboldii Miq.,Clematis chinensis Osbeck.and C.hexapetala Pall.on non-specific immunity,and further determine the feasibility of Smilax sieboldii Miq.to be used as drug. Methods The carbon granules clearance test in mice and chicken red blood cell phagocytosis test were carried out to compare the effects. Results All of Smilax sieboldii Miq.,Clematis chinensis Osbeck.and C.hexapetala Pall.inhibited the phagocytic function of monocyte-macrophage and abdominal cavity macrophage in mice,and reduced non-specific immune function. Conclusion Smilax sieboldii Miq.can be used equivalently as Clematis chinensis Osbeck.for the treatment of rheumatism.