白细胞介素8与早产的关系

The Relations hip Between Interleukin 8 And Premature Brith

目的 通过测定宫颈粘液中白细胞介素８（ＩＬ－８）的浓度及中性粒细胞数，探讨早产与感染的关系。 方法 用酶联免疫吸附（ＥＬＩＳＡ）法，对８２例先兆早产孕妇（研究组）和１０４例正常孕妇（对照组）宫颈粘液中ＩＬ－８进行检测，ＩＬ－８≥４５０ μｇ／Ｌ为阳性；在４００倍显微镜下对４９例先兆早产孕妇及１０４例正常孕妇宫颈粘液中中性粒细胞数进行检测。 结果 研究组孕妇宫颈粘液中，ＩＬ－８阳性率及中性粒细胞数明显高于对照组。 结论 通过此研究提示早产与生殖道感染有一定的关系。

Objective To study the relations hip between premature birth and infection through interleukin 8 (IL 8) level in and counting the number of level neutrocyte in cervicel secretion. Methods IL 8 was measured by enzyme labeled immunosorbent (ELISA) methods in cervical secretion from 82 women with threatened preterm delivery (study group) and 104 normal pregnanty women with same gestational week (control group). The number of neutrocyte in cervical secretion was counted with microsope of ×400. Results The postive rate of IL 8 and neutrocyte in study group was significantly higher than those of the control group. Conclusions Premature birth is related to the infection of reproductive duct. It is a very efficient method to examine the conc entration of IL 8 in cervical secretion for predicting and controlling the premature birth.