子宫肌瘤患者子宫切除术后卵巢功能的变化

The effect of hysterectomy on ovarian function of patients with uterine tumor

目的观察子宫肌瘤患者行子宫切除术后卵巢功能的变化。方法选择需行子宫切除的子宫肌瘤患者64例,分为全切组与次全切组,分别于术前、术后1个月和6个月测定患者的性激素水平。结果全切组和次全切组的E2水平在术后1个月时低于术前(P<0.05),但在术后6个月时则与术前无差异(P>0.05)。两组患者术后1个月时的FSH、LH水平均分别较术前上升(P<0.05),但术后6个月时的FSH、LH与术前水平相近(P>0.05)。两组的3种性激素浓度在术后1个月和6个月时无差异(P>0.05)。结论全子宫切除术与次全子宫切除术对卵巢的近期功能无明显影响。

Objective To observe impact of hysterectomy on recent ovarian function in the women who suffered from uterine tumor.Methods Before operation,one month and six months after operation sexual hormone concentrations（LH,FSH and E2）were respectively determined in 64 women with uterine tumor having been divided into total hysterectomy group and subtotal hysterectomy group.Results There was a significant difference in E2 concentrations of two groups before operation and one month after operation（P0.05）,but no significant difference was found six months after operation.One month after operation,the levels of LH and FSH increased in two groups compared with those before operation,but the levels of the two hormones returned to the levels before operation at the end of six months after operation.There were no significant differences in the concentrations of LH,FSH and E2 between two groups one month and six months after operation.Conclusion Suggestion of this study is that the recent ovarian function has no apparent change after total and subtotal hysterectomy.