左旋精氨酸联合硫酸镁治疗妊娠期高血压病的疗效观察

Efficacy of L-arginine combined with magnesium sulfate in treating gestational hypertension

目的探讨左旋精氨酸联合硫酸镁治疗妊娠期高血压病的临床治疗效果。方法将106例妊娠期高血压病患者随机分为观察组和对照组。观察组给予静脉滴注左旋精氨酸和硫酸镁治疗,对照组仅静脉滴注硫酸镁,观察两组患者的疗效及不良反应。结果观察组的不良反应(烦躁、头晕、胸闷和心率加快)发生率明显低于对照组(P<0.01)。结论左旋精氨酸联合硫酸镁治疗妊娠期高血压病的效果比较好。

Objective To assess the effect of the L-arginine combined with magnesium sulfate（MgSO4） on gestational hypertension.Methods One hundred and sixty pregnant women were randomized into observation group and control group.The former group was treated via intravenous drop of L-arginine and MgSO4,but the late was only done with MgSO4.The effectiveness and adverse reaction in both groups were recorded.Results A low rate of side effects including increased heart rate,the fidgets etc.existed in observed group as compared with the control one（P0.01）.Conclusion These results suggest that L-arginine combined with magnesium sulfate have a better effect on pregnancy-induced hypertension.