期刊文献+

曲美他嗪治疗糖尿病合并冠心病120例临床分析 被引量:1

原文传递
导出
摘要 目的:探讨曲美他嗪治疗糖尿病合并冠心病的临床疗效。方法:选取糖尿病件冠心病患者240例,随机分成观察组和对照组,对照组患者采用常规冠G病药物治疗,观察组患者在常规治疗基础上加用曲美他嗪进行治疗,经过一个疗程的治疗后,分析两组患者的治疗效果。结果:曲美他嗪组疗效较常规治疗组疗效好,差异显著,有统计学意义。结论:曲戋他嗪的疗效机制较适合糖尿病合并冠心病患者的治疗,即能有效改善心肌缺血的状况,同时对糖尿病本身也有改善作用,值得临床推广应用。
作者 龚军 刘永志
出处 《按摩与康复医学》 2011年第20期105-105,共1页 Chinese Manipulation and Rehabilitation Medicine
  • 相关文献

参考文献3

  • 1郭丽娜.曲美他嗪治疗2型糖尿病合并心力衰竭的疗效观察[J].中国基层医药,2010,17(8):1039-1040. 被引量:11
  • 2邹晓霞 但三利.曲美他嗪对糖尿病心肌病患者的保护效应[J].中国基层医药,2009,16:2-2.
  • 3Brottier L, Baart J L, Combe C, et al. Thereapeutic value offl cardio protective agent in patients with sever ischemiccardiomyopathy[J] Eur Heart J,1999,11-207.

二级参考文献10

  • 1Fein FS,Sonnenblick EH.Diabetic cardiomyopathy.Cardiovasc Drugs Ther,1994,8(1):65-73.
  • 2Belardinelli R,Purcaro A.Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathy.Eur Heart J,2001,22(23):2164-2170.
  • 3Fang ZY,Sharman J,Prins JB,et al.Determinants of exercise capacity in patients with type 2 diabetes.Diabetes Care,2005,28(7):1643-1648.
  • 4Chazov EI,Lepakchin VK,Zharova EA,et al.Trimetazidine in Angina Combination Therapy-the TACT study:trimetazidine versus conventional treatment in patients with stable angina pectorisina randomized,placebo-controlled,multicenter study.Am J T-her,2005,12 (1):35-42.
  • 5Grynberg A.Modifications inmyocardial enerymetabolism in diabetic patients.Diabetes Metab,2001,27(5 Pt2):S12-S19.
  • 6Kantor PF,Lucien A,Kozak R,et al.The antianginal drug trimetazidine shifts cardiac energymetabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme a thiolase.Circ Res,2000,86 (5):580-588.
  • 7Sentex E,Helies-Tussaint C,Rousseau D,et al.Influence of trimetazidine on the synthesis of comp lex lip ids in the heart and other target organs.Fundam Clin Pharmacol,2001,15 (4):255-264.
  • 8Dinapoli P,Tacacrdi AA,Barsutti A.Zong term cardio protective action of trimetazidinl and potential ehect on the imflammatory process in patients with ischaemic dilated cardiomy opatuy.Heart,2005,91 (2):161-165.
  • 9Allibardi S,Chierchia SL,Margonato V,et al.Effects of trimetazidine on metabolic and functional recovery of postischemic rat hearts.Cardiovasc Drugs Ther,2001,12 (6):543-549.
  • 10王爱民,郧立杰,王建军.曲美他嗪治疗冠状动脉粥样硬化性心脏病心力衰竭患者临床观察[J].河北医药,2009,31(14):1785-1786. 被引量:2

共引文献11

同被引文献15

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部