早产儿脑室周围白质软化临床高危因素分析

目的分析探讨早产儿脑室周围白质软化发生的高危因素。方法回顾性分析2008年1月至2010年1月期间在我院治疗的22例确诊为PVL的早产儿的临床资料。结果早产儿PVL的发生与胎龄、出生体质量、窒息、肺透明膜病、呼吸暂停、呼吸衰竭、感染、机械通气、胎膜早破、低血糖、肺出血、低血压、贫血、凝血异常等多种因素有密切关系。结论 PVL发生与多种因素密切相关,头部B超可对早产儿PVL做出早期诊断。

Objective To investigate the high risk factors of the periventricular leukomalacia in preterm infants.Methods A retrospective analysis of clinical data was conducted in 22 preterm infants with periventricular leukomalacia who were admitted in our hospital from January 2008 to January 2010·Results The incidence of PVLwas negatively related to conceptus age,birth weight,apnoea,hyaline membrane disease,breathing holding,respiratory failure,infextation,mechanical ventilation,premature rupture of membranes,hypoglycaemia,pneumorrhagia,hypotension,anaemia and disturbance of blood coagulation.Conclusion The incidence of preterminfants is closely related to multiple factors,head ultrasonography is beneficial for early diagnosis of PVL.