血清FSH、LHⅡ、E2检测在更年期妇女中的意义

Value of Measurement of Serum FSH、LHⅡ and E2 levels for menopausal women

目的:探讨血清FSH、LHⅡ、E2检测在更年期妇女中的意义。方法:采用电化学发光法对217例更年期妇女进行血清FSH、LHⅡ、E2测定,并与100名22～35生育年龄妇女对照。结果:更年期组FSH、LHⅡ、E2分别为41.9±17.8mIU/m1、28.6±11.3mIU/m1和27.5±9.2pg/ml,与正常对照组比较,FSH、LHⅡ值明显增高,E2明显降低,差异非常显著(P<0.01)。结论:血清FSH、LHⅡ、E2检测可作为诊断更年期综合征、卵巢早衰的特异性指标。更年期妇女40岁以后每年定期检测FSH、LHⅡ、E2激素水平,对提高生命质量有着重要意义。

Objective：To investigate the diagnostic value of determination of serum FSH,LHⅡ and E2 levels for menopausal women. Methods：Serum FSH,LHⅡ and E2 levels in 217 menopausal women and 100 controls were determined by ELC method. Result：Serum FSH,LHⅡ and E2 levels were 41.9±17.8mIU/m1、28.6±11.3mIU/m1 and 27.5±9.2pg/ml in menopausal women respectively. Compared with the controls,FSH and LH levels in menopausal women increased,E2 level declined. Difference between the values of the two patient groups was significant（P0.01） . Conclusion：Measurement of serum FSH,LHⅡ and E2 levels could be used as a specific parameter for diagnosis of climacteric syndrome and premature ovarian failure（POF） . It＇s of great significance for menopausal women after the age of 40 regular testing FSH,LHⅡ,E2 levels to improve the quality of life.