不同麻醉药物对老年患者全麻术后认知功能的影响比较

The comparison on the influence of different anesthetics for the cognitive function of elderly patients after the general anesthesia

目的:比较不同麻醉药物对老年患者全麻术后认知功能的影响。方法:选取2008年1月～2011年3月于本院进行全麻手术的80例老年患者为研究对象,将其随机分为A组(瑞芬太尼组)40例和B组(芬太尼组)40例,后将两组患者的手术时间、睁眼时间、语言陈述时间及术前、术后1h、6h、12h、24h的MMSE评分进行统计及比较。结果:两组手术时间比较,P>0.05,而A组的睁眼时间、语言陈述时间均短于B组,术后1h、6h、12hMMSE评分高于B组,且P<0.05,均有显著性差异。结论:瑞芬太尼全麻患者术后苏醒较快,认知功能恢复速度也较快,评估效果明显。

Objective：To compare the influence of different anesthetics for the cognitive function of elderly patients after the general anesthesia .Methods：80 elderly patients with the general anesthesia from January 2008 to March 2011 were selected as research object,and they were randomly divided into group A（remifentanil group） 40 cases and group B（fentanyl group） 40 cases,then the operation time,eye opening time,statement time and MMSE score before and after the operation at 1h,6h,12h and 24h were analyzed and compared.Results：The operation time of two groups were compared,P0.05,but eye opening time,statement time of group A were both shorter than those of group B,MMSE score after the operation at 1h,6h,12h were higher than those of group B,all P P0.05,there were significant differences.Conclusion：The analepsia time of remifentani anesthesia is shorter,recovery speed of cognitive function is fast,effects is obvious.