1Zhang W, Wang T, Pei Z, et al. Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease [J]. Faseb J, 2005,19(6):533-542.
2Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: muhiple triggers with a common mecha- nism [J]. Prog Neurobiol, 2005, 76(2):77-98.
3蔡向红.《金匮要略》大黄运用特点[J].北京针灸骨伤学院学报,1997,4(1):15-17.
4金东明.《伤寒论》大柴胡汤有无大黄考[J].中医药学报,1984.12(6):38-40.
5Neumann J, Sauerzweig S, Ronicke R, et al. Microglia cells protect neurons by direct engulfment of invading neutrophil granulocytes: a new mechanism of CNS immune privilege[J]. J Neurosci,2008,28(23):5965-5975.
6Karlstetter M, Walczak Y, Weigelt K, et al. The novel acti- vated microgha/macrophage WAP domain protein, AMWAP, acts as a counter-regulator of proinflammatory response [J]. J Immunol, 2010, 185(6):3379-3390.
7Neumann H, Kotter MR, Franklin RJ. Debris clearance bymicroglia: an essential link between degeneration and regen- eration [J]. Brain,2009,132(2): 288-295.
8Wang T, Liu B, Zhang W, et al. Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cuhures by inhibiting microglial activation[J]. J Pharmacol Exp Ther, 2004,308(3):975-983.
9Jang S, Kelley KW, Johnson RW. Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1 [J]. Proc Natl Acad Sci USA, 2008, 105(21):7534-7539.
10Suk K, Lee H, Kang SS, et al. Flavonoid baicalein attenu- ates activation-induced eel1 death of brain mieroglia[J]. J Pharmaeol Exp Ther, 2003, 305(2):638-645.