期刊文献+

生长激素在体外受精-胚胎移植中对卵巢反应不良患者的影响 被引量:4

下载PDF
导出
摘要 目的:在体外受精-胚胎移植(IVF-ET)的COH过程中,观察并探讨促性腺激素(Gn)联合使用生长激素(CH)对卵巢反应不良患者治疗效果的影响。方法:选择2010年3月至2010年11月在我生殖中心接受IVF/ICSI治疗的80例患者,将其分为2组:Gn联合应用GH的40例患者为研究组,只使用Gn的40例患者为对照组,比较两组获卵数及成熟卵母细胞数、受精率、卵裂率、获胚胎数目、优质胚胎数以及妊娠率的差异。结果:研究组获卵数及成熟卵母细胞数、获胚数、优胚数上均比对照组提高,但是差异没有统计学意义;受精率、妊娠率P〈0.05,差异有统计学意义。结论:卵巢反应不良患者在IVF-ET的COH中Gn联合应用GH可以提高受精率及临床妊娠率,改善IVF—ET结局。
作者 牛芳 李柳铭
出处 《中国中医药咨讯》 2011年第18期418-419,共2页
  • 相关文献

参考文献4

  • 1朱小明,蔡婕,黄荷凤.卵巢低反应的诊断标准和预测[J].中国实用妇科与产科杂志,2006,22(5):388-390. 被引量:50
  • 2覃爱平.超排卵卵巢反应不良原因及评估处理[J].广西医学,2005,27(11):1808-1809. 被引量:5
  • 3Priya B.Maseelall, M.D, Armando E.Hernandez-Rey.Antral follicle count is a significant predictor of livebirth in in vitro fertilization cycles [J]. Fertil Steril, 2009,91:1595 1597.
  • 4Hansen LM. Batzer FB. Gutmann JN et 01. Evaluation ovarian reserve :Folicle stimulating horm one and estradiol variability during cycle days 2 - 5[J]. Hum Reprod, 1996,11(2):486 - 489.

二级参考文献36

  • 1Kailasam C, Keay SD, Wilson p, et al. Defining poor ovarian response during IVF cycles, in women aged 40years, and its relationship with treatment outeome[J].Hum Repro,2004,19(17):1 544~ 1 547.
  • 2Ben-Rafael Z, Bider D, Dan U, et al. Combined gonadotropin releasing hormone agonist/human menopausal gonadotropin therapy (GnRH/HMG) in normal high and poor responder to hMG[J] .J in Vitro Fert Embryo Transt,1991,8(1) :33.
  • 3Faddy MJ, Gosden RG, Gougen A, et al . Accelerated disappearance of ovarine follicles in mid-life: implication for forescasting menophause[J]. Hum Reprod,1992,7(10): 1 342~ 1 346.
  • 4Keay SD, Liversedge NH, Mathur RS, et al. Assisted conception following ovarian response to gonadotrophin[J]. Br J Obstet Gynaecol, 1997, 104(5) :521 ~ 527.
  • 5Keay SD, Barlow R, Eley A, et al The relation between immuoglobulin Gantibodies to chlamydia trachomatis and poor ovarian response to gonadotrophin stimulation before in vitro fertilazition[J]. Fertil Sertil, 1998,70(2):214 ~ 218.
  • 6Tanbo T,Abyholm T, Bjoro T,et al. Ovarian stimulation in previous from in vitro fertilization: distinction of two groups of poor responders[J]. Hum Reprod,1990,5(7):811 ~ 815.
  • 7Smotrieh DB,W idra EA,Gindof PR, et al.Prognostic value 0 day 3 estradiol on IVF outcome[J]. Fertil Steril, 1995,64(6): 991 ~ 994,1 136~1140.
  • 8Ubaldi FM, Rienzi L, Ferrero S, et al. Management of poor responder in IVF[J]. Reprod Biomed Online.2005 , 10(2) :235 ~ 246.
  • 9Khalaf Y, EL-Ttoukhy T, Taylor A, et al. Increasing the gonadotrophin dose in the course of an in vitro fertilization cycle does not rectify an initial poor response. Eur, J Obstetric Gynecol[J]. Reprod Biol, 2002, 103(2): 146 ~ 149.
  • 10Klinkert ER, Broekmans FJ, Looman CW, et al. Expected poor responders on the basis of an antral follicle count do not benefit from a higher starting does of gonadotrophins in IVF treatment: a randomized controlled trial[J] .Hum Reprod,2005,20(3): 611~615.

共引文献53

同被引文献37

  • 1张洁,谭丽,项云改.生长激素对小鼠增殖期子宫内膜厚度及VEGF EGF IGF-I表达的影响[J].医药论坛杂志,2006,27(24):13-15. 被引量:8
  • 2Chandrashekar V, Zaczek D, Bartke A. The consequences of alteredsomatotropic system on reproduction[J]. Biol Reprod, 2004,71 : 117-127.
  • 3Joyee IM,Khalid M, Haresign W. The effect of recombinant GH treatment on ovarian growth and atresia in sheep[J]. Theriogenology, 2000,54 : 327- 338.
  • 4Kiapekou E, Loutradis D,Drakakis P, et al. Effects o GH and IGF-I on the invitro maturation of mouse oocytes [J]. Endocrinology, 2005,4 : 155-160.
  • 5Tesarik J, Hazout A, Mendoza C. Improvement of delivery and live birth rates after ICSI in women aged40 years by ovarian co-stimulation with growth hormone [-J ]. HumReprod. 2005,20:2516-2541.
  • 6Rajesh H, Yong YY, Zhu M, et al. Growth hormone deficiency and supplementation at in-vitro fertilization [J]. Singapore Med J, 2007,4,8 : 514-518.
  • 7Kolibianakis EM,Venetis CA,Diedrich K, et al. Addition of growth hormone togonadotrophins in ovarian stimulation of poor responders reared by in-vitro fertilization:a systematic review and meta-analysis[J]. Hum Reprod Update, 2009,15: 613-622.
  • 8Eftekhar M, Aflatoonian A, Mohammadian F, et al. Adjuvant growth hormone therapy in antagonist protocol in poor responders undergoing assisted reproductive technology[J]. Arch Gynecol Obstet,2013,287:1017-1021.
  • 9Mallei L, Rochira V, Zirilli L, et al. A novel compound heterozygous mutation of the aromatase gene in adult man: reinforced ev-idence on the relationship between congenital oestrogen deficiency, adiposity and the metabolic syndrome [J]. Clin Endocrinol, 2007,67 : 218-224.
  • 10李国涛,齐玲玲,刘振蛾.生长激素在体外受精超排卵中的临床应用效果观察[J].潍坊医学院学报,2008,30(1):56-57. 被引量:3

引证文献4

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部