高血压前期人群血压转归及其影响因素的调查分析

目的探讨高血压前期人群血压转归情况及其影响因素。方法选择2007年1月-2008年12月在本院体检符合高血压前期诊断标准的高血压前期人群1564例作为观察队列。于2009年1月-2010年12月对观察队列进行第2次健康体检,了解其血压转归情况及其影响因素。结果各种原因失访329例,观察队列第2次休检人数为1235例。高血压前期人群2年后进展至高血压的比例为32.96%(407/1235),男性高血压前期人群2年后进展至高血压的比例为35.34%(346/979),女性为23.82%(61/256)。经多因素分析,患者收缩压(SBP)、舒张压(DBP)、腰围、年龄、体重、性别、总胆固醇(TC)、空腹血糖(FBG)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C),其OR值>1,以上均为影响高血压前期患者血压转归的因素。结论应加强对高血压前期人群的关注,针对影响高血压转归的因素进行干预,通过提高高血压前期人群疾病防治知识,改变其不良的生活方式,从而减少心脑血管等并发症的发生进而阻止高血压前期的进展。

Objective To explore the turnover of blood pressure and its relative risk factors in the early stage of high blood pressure.Methods Patients in the early stage of high blood pressure who received physical examination from January 2007 to January 2008 in our hospital were selected.The patients received physical examination again from January 2009 to January 2010.The turnover of blood pressure and its relative risk factors were observed.Results Two years later,35.34%（346/979） of patients of the males and 23.82%（61/256） of the females） progressed into high blood pressure.Patients＇ systolic pressure,diastolic pressure,waistline,age,body weight,gender,total cholesterol,fasting blood glucose,triglyceride,and high-density lipoprotein were among the risk factors that influence the turnover of blood pressure.Conclusion To check the disease development and to reduce complications,people in the early stage of high blood pressure should be paid great attention;risk factors should be intervened;patients＇ prevention and cure knowledge should be improved;and bad lifestyle should be altered.