肺泡表面活性物质用于早产儿呼吸窘迫综合征治疗的护理

Clinical nursing of pulmonary surfactant in treatment of premature babies with respiratory distress syndrome

目的探讨肺泡表面活性物质治疗早产儿呼吸窘迫综合征的疗效和护理对策。方法2008年7月至2011年1月共收治早产儿呼吸窘迫综合征患儿63例，向患儿的气管内滴入肺泡表面活性物质，观察用药后的疗效。结果63例患儿有1例因合并呼吸衰竭死亡，1例因合并肺出血死亡，余61例治愈出院，治愈率为96．8％。61例治愈的患儿，治疗后动脉血pH、氧分压（Pa02）、血氧饱和度（SaO2）显著高于治疗前。治疗后动脉血二氧化碳分压（PaCO2）、二氧化跳总量（TC02）、实际碳酸氢盐（AB）显著低于治疗前。结论肺泡表面活性物质联合适宜的护理措施能有效地治疗早产儿呼吸窘迫综合征。

Objective To investigate the therapeutic effect and nursing ways of pulmonary surfactant in premature babies with respiratory distress syndrome. Methods From July 2008 to January 2011, 63 cases of premature babies with respiratory distress syndrome were admitted to our department, pulmonary surfactant was dripped through trachea into these patients, the treatment effect after medication was observed. Results Among these premature babies, one case died of respiratory failure, one case died from pulmonary hemorrhage, sixty-one cases were cured, the cure rate was 96.8%. After treatment, the arterial blood pH, partial pressure of oxygen（PaO2） and oxygen saturation（SaO2） of the 61 patients was significantly higher than before treatment, the arterial blood partial pressure of carbon dioxide （PaCO2）,total carbon dioxide（TCO2）,actual bicarbonate（AB）was significantly lower than before treatment. Conclusions Pulmonary surfactant combined with appropriate nursing ways is able to cure premature babies with respiratory distress syndrome effectively.