苦参碱注射液对急性病毒性心肌炎的治疗作用

Matrine Injection for Acute Viral Myocarditis

目的:观察苦参碱注射液治疗急性病毒性心肌炎(AVM)的临床疗效。方法:将AVM患者120例随机分为治疗组63例及对照组57例,对照组采用常规疗法,治疗组在对照组基础上给予苦参碱注射液治疗,连用2周。观察临床疗效。结果:治疗组总有效率90.5%,对照组总有效率73.7%,两组比较有显著性差异。治疗组治疗后血清肌酸磷酸激酶(CPK)、天冬氨酸转氨酶(AST)及血清乳酸脱氢酶(LDH)较对照组治疗后明显降低,差异有统计学意义(P<0.05)。结论:苦参碱对急性心肌炎有良好疗效。

Objective： To observe the effect of matrine injection in the treatment of patients with acute viral myocarditis（AVM）.Methods： A total of 120 patients with AVM were randomly divided into treatment group（n=63） and control group（n=57）.The control group was given the conventional therapy;the treatment group,matrine injection plus the conventional therapy for two weeks.The clinical treatments of the two groups were observed.Results： The total effective rate of the treatment group was 90.5%;The total effective rate of the control group was 73.7%.Serum creatine phosphokinase（CPK）,aspartate aminotransferase（AST） and serum lactate dehydrogenase（LDH） were reduced in the treatment group compared with the control group.There was significant difference between the two groups（P0.05）.Conclusion： Matrine has a good effect on acute myocarditis.