婴幼儿轮状病毒感染情况调查

Investigation of the rotavirus infection situation of infants

目的了解本地区婴幼儿A组轮状病毒(RV)的感染状况。方法采用免疫层析双抗体夹心法对山东省东营市第二人民医院2009年11月至2010年10月收治的432例婴幼儿腹泻患儿的粪便标本进行A组RV抗原检测。结果在432份婴幼儿腹泻患儿的粪便标本中共检出RV阳性标本157例,阳性率为36.3%;其中在2、3月份共有86例RV阳性粪便被检出,占54.8%,在6个月至2岁年龄段的婴幼儿中有92例RV阳性标本,占58.6%,被检出的157例RV阳性标本中有男性患儿83例,占52.9%;女性患儿74例,占47.1%。结论 A组RV是引起的婴幼儿急性腹泻的主要病原,每年冬季11月到次年1月份最为集中,其中6个月至2岁年龄段为婴幼儿A组RV感染的高峰期。

Objective To understand rotavirus（RV） infection status of infants.Methods By immune chromatography double antibody sandwich-ELISA,we tested the antigen of human RV from feces samples of infants with diarrhea in our hospital from November 2009 to October 2010.Results 157 out of 432 feces samples were found the RV,and the positive rate of RV was 36.3%.86 cases of RV positive feces were found out in February and March,accounted for 54.8%,92 cases of RV positive feces of 0.5 to 2 years old infants accounted for 58.6%.Among the 157 RV positive specimens,male children were 83 cases,accounted for 52.9 %,female children accounted for 47.1%（74/157）.Conclusion Group A rotavirus is the main pathogen caused the infant acute diarrhea,and has a high infection rate from November to next January,there is a peak period of infection among the 6 months to 2 years old infants.