左氧氟沙星治疗HBV携带肺结核患者疗效观察

The effect of levofloxacin on pulmonary tuberculosis patients with hepatitis B virus carried

目的探讨左氧氟沙星治疗乙肝病毒(HBV)携带的肺结核患者临床疗效及安全性。方法 97例HBV携带的肺结核患者,随机分为治疗组50例,予以3HREV/6HR治疗;对照组47例,予以3HRZE/6HR治疗。结果治疗组肝功能损害几率为24.0%,对照组肝功能损害几率为48.9%,两组差异有显著性(P<0.05)。治疗组抗结核总有效率92.0%,对照组总有效率93.6%,抗结核化疗总有效率无显著性差异(P>0.05)。结论左氧氟沙星治疗HBV携带的肺结核患者疗效好,肝毒性小,值得临床推广。

Objective To observe the effect of levofloxacin on pulmonary tuberculosis patients with hepatitis B virus carried.Methods 97 pulmonary tuberculosis patients with hepatitis B virus carried were randomly divided into two groups.Treatment group received the treatment scheme of 3HREV/6HR and control group received the treatment scheme of 3HRZE/6HR.Results The liver injury rates of treatment group and control group were 48.9% and 24.0%,respectively（P0.05）.The total effective rates of treatment group and control group were 93.6% and 92.0%（P0.05）.Conclusion There is significant effect of levofloxacin on pulmonary tuberculosis.