血气分析在诊断尿毒症患者中的临床价值

The clinical value of blood gas analysis in diagnosis of uremic patients

目的:探讨分析血气分析在早期诊断尿毒症患者中的临床价值。方法:对172例患者进行回顾性分析,其中正常对照组60例,氮质血症组60例,尿毒症组52例。结合临床实际对比分析各组血气分析指标异常情况。结果:氮质血症组出现代谢酸中毒,其pH、PaCO2、HCO3-均比正常组有所降低(P<0.05),PaO2、SaO2虽较正常组有所降低,但都在正常范围内,且其PaCO2属于代偿性降低。尿毒症组则显示出明显的失代偿性代谢性酸中毒,PaO2轻度降低,部分患者出现CO2潴留。其血气分析指标紊乱程度均高于氮质血症组(P<0.05)。结论:血气分析异常指标及其强弱程度与肾脏的受损程度密切相关,血气分析有助于早期发现及诊断尿毒症患者,应在目前的医疗基础上加强尿毒症患者的常规血气分析检查。

Objective： To analyze the clinical value of blood gas analysis in early diagnosis of uremic patients. Methods： Retrospectively analyzed the clinical data of 172 patients. 60 cases of normal control group, 60 patients of Nitrogen quali- tative hematic disease group, 52 cases uremic patients group. Comparativly analyzed of blood gas analysis in the difference between the groups combined with clinical. Results： Azotemia group showed metabolic acidosis, the pH, PaCO2, HCO3- decreased than normal group （P〈0.05）, the PaO2, SaO2, although somewhat lower than the normal group, but all within the normal range, and the PaCO2 was reduced compensatory. Uremic group showed significantly decompensated acidosis, Pa02 decreased slightly, some patients had CO2 retention. The degree of blood gas analysis disorder were higher than azotemia （P〈0.05）. Conclusion： Abnormal blood gas analysis indicators and their intensity level is closely related with kidney damage, blood gas analysis would be help for earlier detection and diagnosis of patients with uremia, uremic patients should be strengthened inspection routine blood gas analysis.