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氨氯地平联合阿托伐他汀治疗原发性高血压的疗效 被引量:9

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摘要 目的:探讨氨氯地平联合阿托伐他汀治疗原发性高血压的临床疗效。方法:选取本院2007年9月~2010年8月收治的80例原发性高血压患者的临床资料,将其随机分为治疗组40例和对照组40例,对照组患者应用氨氯地平进行治疗,治疗组患者在对照组治疗的基础上加用阿托伐他汀,连续治疗4周,比较两组的血压变化情况。结果:治疗组患者降压效果明显优于对照组,两组比较,差异有统计学意义(P<0.05)。结论:氨氯地平联合阿托伐他汀治疗原发性高血压,具有协同作用,药物安全性高,减小心血管事件的发生率,疗效满意,值得在临床推广。
出处 《中国当代医药》 2011年第20期42-42,共1页 China Modern Medicine
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  • 1张维忠,邱慧丽,范明昌,龚兰生.高血压左心室肥厚的诊断探讨——5437例超声心动图资料分析[J].中国高血压杂志,1993,1(1):5-8. 被引量:87
  • 2施仲伟,沈蓓蓓,沈戈,林淑英,龚兰生.正常老年人颈动脉壁厚度及超声多普勒血流参数测定[J].中国超声医学杂志,1995,11(10):737-739. 被引量:39
  • 3Tea B, Sarkissian SD, Touyz RM et al. Proapoptotic and growth-inhibitory role of angiotensin Ⅱ type 2 receptor in vascular smooth muscle cells of spontaneously hypertensive rats in vivo[J].Hypertension,2000, 35:1069-1073.
  • 4Dervereux RB, Alonao ER, Lutas EM, et al. Echocardiographic assessment of left ventricular hypertrophy: comparism to necropsy findings[J].Am J Cardiol,1986, 57:450-458.
  • 5Ganau A, Devereux RB, Roman M, et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension[J].J Am Coll Cardiol,1992,19:1550-1560.
  • 6Zierhut W, Studer R, Laurnt D, et al. Left ventricular wall stress and sarcoplasmatic reticulum Ca2+-ATPase gene expression in renal hypertensive rats: dose-dependent effects of ACE inhibition and AT1-receptor blockade[J].Cardiovasc Res,1996,31:758-768.
  • 7Kojima M, Shiojima I, Yamazaki T, et al. Angiotensin Ⅱ receptor antagonist TCV-116 induces regression oh hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro[J].Circulation,1994,89:2204-2211.
  • 8Graven TE, Ryu JE, Espeland MA, et al. Evaluation of the association between carotid artery atherosclerosis and coronary artery sterosis: a case-control study[J].Circulation,1990,82:1230-1242.
  • 9Ferrars LA, Mancini M, Lannuzzi R, et al. Carotid diameter and blood flow velocities in circulation in hypertensive patients[J].Stroke,1995,26:418-421.
  • 10Thybo NK, Stephens N, Cooper A, et al. Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension[J].Hypertension,1995,25:474-481.

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