泌尿系感染的病原菌分布及耐药性分析

Distribution and Antibacterial Resistance of Pathogenic Bacteria in Respiratory Tract Infection

目的:了解泌尿系感染患者病原菌的分布及其耐药性,以指导临床合理用药。方法:对2009年10月-2010年12月尿路感染患者525株病原菌进行鉴定和药敏试验。结果:泌尿系感染的病原菌以G-杆菌为主,占67.4%,其中肠杆菌科细菌占63.4%;其次是G+菌,占20.6%;真菌占12.0%。肠杆菌科细菌对亚胺培南、头孢哌酮/舒巴坦、哌拉西林/他唑巴坦的耐药率较低,小于1%;G+球菌对万古霉素和呋南妥因有较高的敏感性,在90%以上。结论:泌尿系统感染仍以肠杆菌科细菌为主,但球菌和真菌感染的比例升高,致病菌的耐药率上升,临床医生应加强对泌尿系感染患者的病原菌检测及耐药性的监测,合理使用抗生素。

Objective：To understand the term＇s type and its antibiotic resistance in the patients with urinary tract infection for instructing the reasonable use of the medicine.Methods：Totally 525 isolates collected from uruary infection specimens were identified and drug susceptibility test was performed from October 2009 to December 2010.Results：Gram-negative was still the most common pathogen in ufinary tract infection.Its isolation rate was about 67.4%.The enterobacteriaceae rate was about 63.4%.Gram-positive bacteria for 20.6%,and epiphyte for 12.0%.The enterobacteriaceae drug resistance to imipenem,piperacilintazobactam,Cefoperazone-sulbactam was lower than 1%.And Gram-positive bacteria showed high susceptibility to vancomycin,nitrofurantoin,higher than 90.0%.Conclusion：Urinary tract infection still take the enterobacteriaceae as the focus,but the proportion of coccus and epiphyte elevates,the germ antibiotic resistance rate is rising.