神经外科重症患者血糖水平与预后的关系

Relationship of hyperglycemia with neurological outcome after severe brain injury

目的分析脑损伤后高血糖对神经外科重症患者预后的影响。方法依据病例纳入标准,回顾性分析纳入研究的94例患者临床资料。根据格拉斯哥预后评分(GOS),将94例患者分为预后较好组(61例)和预后较差组(33例),分析两组之间伤后血糖水平与预后的关系。结果伤后血糖(包括入院及术后血糖)比较,预后较好组较预后较差组低,两组比较差异有统计学意义(P<0.05)。结论神经外科重症患者伤后高血糖与疾病预后密切相关;高血糖可作为预测神经外科重症患者预后的早期指标。

Objective To observe the effect of hyperglycemia on neurological outcome following severe brain injury.Methods A retrospective review was done on 94 patients with severe traumatic brain injury（without history of diabetes or important extracranial complications） who underwent craniotomy for evacuation of intracranial hematoma and were divided into two groups based on Glasgow outcome scales（GOS） score,favorable group and unfavorable group.Results A significant correlation was found between outcome and admission or postoperational glucose values.The unfavorable group had significantly higher glucose levels both on admission and postoperational compared with the favorable group,with statistical difference（P0.05）.Conclusion Hyperglycemia is positively correlated with out-come,and the serum glucose level can be used as early and simple prognostic indicator.