摘要
目的探讨慢性乙肝患者重叠急性戊肝对临床转归的影响。方法将55例慢性乙肝患者分成两组,一组25例为乙肝合并戊肝急性感染,另一组30例为单纯慢性乙肝组,对两组进行临床特点的对照分析。结果乙肝合并戊肝急性感染组黄疸深[TB(319.78±153.94)μmol/L)],血清白蛋白更低[(33.39±5.17)g/L],凝血功能恶化[PTA(52.92±28.04)%],重肝发生率(40%)、并发症发生率(32%)及死亡率(12%)均明显高于单纯乙肝组(P<0.05)。结论慢性乙肝重叠戊肝急性感染可诱发慢性肝炎活动及重症化,并发症增多,病死率高,预后差。
Objective To investigate the influence of the clinical outcomes of patients with chronic hepatitis B superinfected hepatitis E virus. Methods 55 patients with chronic hepatitis B were divided into two groups： one group of 25 cases with chronic hepatitis B superinfected hepatitis E virus, and the other group of 30 cases of simple chronic hepatitis B, the clinical features of the two groups were compared. Results In the HBV/HEV superinfection group the patients had deeper level of total serum bilirubin [TB （319.78 ± 153.94）/μmol / L）], lower serum albumin [（33.39 ± 5.17） g/L], coagulation fimction deterioration [PTA （52.92 ± 28.04）%], the incidence of severe hepatitis （40%）, the complication rate （32%） and the mortality rate （12%） were significantly higher than those in the simple hepatitis B group （P〈0.05）. Conclusion Superinfection of HBV and HEV can cause the activity of chronic hepatitis B and more severe hepatitis, higher mortality, more complications and poorer prognosis.
出处
《临床医学工程》
2011年第7期1042-1043,共2页
Clinical Medicine & Engineering
