期刊文献+

慢性萎缩性胃炎的胃黏膜保护机制的研究进展 被引量:6

Research Progress on the Mechanism of Gastric Mucosa Protection of Chronic Atrophic Gastritis
下载PDF
导出
摘要 慢性萎缩性胃炎是慢性胃炎的一种类型,其胃黏膜组织学病理表现为黏膜炎症、腺体萎缩、肠上皮化生和异型增生,而肠上皮化生被认为是萎缩的典型标志以及胃癌的前兆。胃黏膜保护机制可能与抑制胃酸分泌、抵抗H.pylori感染及热休克蛋白的启动等胃黏膜保护因子有关,热休克蛋白在抵御黏膜损害中起重要作用。 Chronic atrophic gastritis is a type of chronic gastritis, with histopathologic experssion as mucosa inflammation, gland atrophy, intestinal metaplasia and dysplastic, and intestinal metaplasia is considered to be typical signs of atrophy and precursor lesions. The mechanism of gastric mucosa protection of chronic atrophic gastritis may be relate to gastric mucosa protective factors such as gastric acid secretion inhibition, H.pylori infection resistance and heat shock protein start, of which heat shock protein is the most critical factor in resistance of gastric mucosal damage.
作者 王权华
出处 《临床医学工程》 2011年第7期1146-1147,共2页 Clinical Medicine & Engineering
关键词 慢性萎缩性胃炎 胃黏膜保护 H.PYLORI 热休克蛋白 Chronic atrophic gastritis Gastric mucosa protection H.pylori Heat shock protein
  • 相关文献

参考文献15

  • 1中国慢性胃炎共识意见[J].胃肠病学,2006,11(11):674-684. 被引量:833
  • 2萧树东.慢性胃炎[M]//叶任高.内科学.5版.北京:人民卫生出版社,2000:392-396.
  • 3吴改玲,蓝宇,王杞.胃镜与病理诊断慢性萎缩性胃炎相关性的调查[J].中华消化内镜杂志,2004,21(2):120-121. 被引量:19
  • 4Kuipers EJ,, Klinkenberg Knol EC, Vandenbroucke Grauls CM, Ap- pelmelk B J, Schenk BE, Meuwissen SG. Role of Helicobacter pylori inthe pathogenesis of atrophic gastritis [J] . Scand J Gastroenterol Suppl, 1997, 223: 28-34.
  • 5Arkkila PE, Seppala K, Farkkila MA, Veijola L, Sipponen P. He- lieobacter pylori eradication in the healing of atrophic gastritis: a one- year prospective study [J] . Scand J Gastroenterol, 2006, 41 (7) : 782-790.
  • 6Rugge M, Shiao YH, Correa P, Baffa R, DiMario F. Immunohistochem- ical evidence of p53 over expression in gastric epithelial dysplasia [J] . Cancer Epidemiol Biomarkers Prev, 1992, 1 (7) : 551-554.
  • 7Wang J, Chi DS, Kalin GB, Sosinski C, Miller LE, Burja I, Thomas E. I-Ielicobacter pylori infection and oncogene expressions in gastric car- cinoma and its precursor lesions [J] . Dig Dis Sci, 2002, 47 (1) : 1077-113.
  • 8Lang L. Barry Marshall 2005 Nobel laureate in medicine and physiolo- gy [J] . Gastroenterology, 2005, 129 (6) : 1813-1814.
  • 9Asaka M, Sugiyama T, Nobuta A, Kato M, Takeda H, Graham DY. At- rophic gastritis and intestinal metaplasia in Japan: results of a large muhieenter study [J] . Helicobacter, 2001, 6 (4) : 294-299.
  • 10Molaei M, Foroughi F, Mashayekhi R, Haghazali M, Zojaji H, Jafari F, Dabiri H, Zali MR. CagA status and VacA subtypes of Helicobacter pylori in relation to histopathologic findings in Iranian population [J] . Indian JPathol Microbiol, 2010, 53 (1) : 24-27.

二级参考文献126

共引文献877

同被引文献99

引证文献6

二级引证文献79

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部