脑卒中发病的时间规律

Time variation of onset of stroke

目的研究脑出血（CH）、脑梗塞（CI）和蛛网膜下腔出血（SAH）的发病时间。方法我们收集了武昌地区1986年10月～1992年10月的急性脑卒中病人1321例，其中CH607例，CI496例，SAH218例。病人发病时间以病人或亲人、同事提供的时间为准，然后比较观察到的实际发病数与24小时期间的理论发病数。结果52．22％的CI、56．OI％的CH和46．33％的SAH在7：01～13：00发病。CH和SAH的发病有季节差异。结论本文结果提示CH、CI和SAH发病的时间与血压的高峰时间重叠，按血压的生理波动，控制好高峰期间的血压，能有效地减少或推迟卒中的发作。本文结果还对CI多发生在睡眠或休息状态，即血压偏低时的传统观点提出了质疑。

To analyze the onset time of cerebral hemorrhage (CH), cerebral infarction (CI) and subarchonid hemorrhage (SAH). Methods From October 1986 to 1992, 1321 patientswith acute cerebrovascular disease of Wuchang area was studied. There were 607 cases of CH, 496 cases of Cl, and 218 cases of SAH. Results 52. 22% of patients with Cl, 56. 01% with CH and 46. 33%with SAH proved onset times between 07: 01 and 13: 00. A seasonal variation was found in the incidenceof CH and SAH, but not in that of CI. Conclusion The onset times of CH, CI and SAH coincide withthe peak interval of blood pressure,and by controlling the blood pressure during the peak interval according to the circadian variation of blood pressure, the onset of stroke may be decreased or delayed effectively. Our data also challenge the traditional view that Cl often occurs during the sleep or at restwhen blood pressure falls.