两种漱口液对口腔挥发性硫化物及舌背细菌的影响

The effect of two kinds of mouthwash on the volatile sulfur compounds and the anaerobic bacteria of tongue dorsum

目的评价常见的两种市售漱口液对口腔挥发性硫化物水平及舌背菌群的影响。方法采用为期1月的单中心、随机、对照、双盲的临床研究方法。研究对象共60人。分为李斯德林漱口液组(A组),高露洁贝齿漱口液组(B组),阴性对照组(C组)。分别在基线、半个月、1个月时检测各组研究对象的口腔挥发性硫化物水平及舌背厌氧菌的数量变化,并进行统计学分析处理。结果对于口腔挥发性硫化物水平,在半个月及1个月时,A组、B组均有明显的下降,均优于C组,差异具有统计学意义(P<0.05);且A组与B组之间的差异也具有统计学意义(P<0.05)。对于舌背厌氧菌的数量变化,在半个月及1个月时,A组、B组厌氧菌数量均有所下降,均优于C组,差异具有统计学意义(P<0.05);但A组与B组之间的差异没有统计学意义(P>0.05)。结论李斯德林漱口液及高露洁贝齿漱口液均能有效降低口腔挥发性硫化物水平及舌背厌氧菌的数量,且李斯德林漱口液降低硫化物的效果更优。

Objective To evaluate the effect of two kinds of mouthwash on the levels of the volatile sulfur compounds and the anaerobic bacteria of tongue dorsum.Method The trial adopted a dual-center,randomized,double-blind,controlled clinical methods,which lasted for one month.A total of 60 subjects were selected and randomly allocated in three groups,Listerine group,Colgate group and placebo group.Recordings were assessed statistically at the baseline,half a month and one month,which included the level of the volatile sulfur compounds and quantitity changes of bacteria of the tongue dorsum.Result At half a month and one month,the Listerine group and Colgate group had a significant reduction in the VSCs scores,which got a better effect in comparison to the placebo group with a significant statistically difference（P〈0.05）,and there was a significant statistically difference between Listerine group and Colgate group.At the same time,the Listerine group and Colgate group resulted in a significant reduction in the total anaerobic bacteria of tongue dorsum,which got a better effect in comparison to the placebo group with a significant statistically difference（P〈0.05）,whereas no significant difference was observed between the two groups.Conclusion The Listerine mouthwash and Colgate mouthwash are both effective in the treatment of the VSCs and the anaerobic bacteria of tongue dorsum,and the Listerine mouthwash has a better performance in reducing volatile sulfur compounds.