极低频电磁场辐射与儿童白血病发病的研究进展

Advances of extremely low-frequency electromagnetic fields and childhood leukemia research

研究表明血液系统恶性肿瘤发病率有逐年增多的趋势，儿童白血病尤为令人瞩目。极低频电磁场辐射与儿童白血病的发生密切相关。极低频电磁场辐射可能通过影响细胞间的信号传导、细胞增殖凋亡、基因表达和DNA损伤等，改变细胞内生物分子物质的大小、形态、数量、化学状态和能量，从而发生级联放大反应，参与儿童白血病的发生。

The increasingly raised morbidity of hematological malignancies have attracted much attention from scientists and clinicians in recent years, especially the childhood leukemia, It has been demonstrated that extremely low-frequency electromagnetic fields is closely related to pediatric leukemia. The extremely lowfrequency electromagnetic fields might change the size, appearance, quantity, chemical state and energy of cellular biological molecules and induce cascade reaction via effects on cell-to-cell signal transduction, cell proliferation and apoptosis, gene expression and DNA damage, ere, subsequently promote the development of childhood leukemia. This paper overviewed the recent advances of relationship between the extremely low- freauenev electromagnetic fields and childhood leukemia.