彩色多普勒血流显像追踪监测腹腔灌注卡铂治疗晚期癌症

Hemodynamic Analysis of Carboplatin Chemotherapy to Treat the Late Stage of Cancer by Abdominal Abministration Using Color Doppler

本文采用彩色多普勒超声显像仪对28例失去手术时机的癌症晚期及术后复发者,进行腹腔灌注卡铂化疗的追踪观察,有效率达100%,经4个疗程的观察,其中16例肿瘤原发灶、转移灶、腹水及肿大的淋巴结完全消失占57.1%;肿瘤原发灶、转移灶、腹水、肿大的淋巴结明显减少者12例占42.9%。CDFI显示肿瘤内部血管完全消失者20例占71.4%;肿瘤内部血管明显减少者8例占29.6%。彩色多普勒超声显像观察肿瘤的原发灶,继发性改变及肿瘤内部的血供情况是指导临床腹腔灌注卡铂用量调整的可靠依据。

Using color doppler ultrasonic angiograph Carboplatin chemotheraply by abdominal abministration in 28 cases of late stage of cancer and postoperative recurrence were studied successfully. The results showed that the effective rate were 100% , during four months course of treatment, the primary focus of tumour, metastasis, ascites and lymphadenectasis were all disappeared in 16 cases (account for 57.1%); while in 12 cases, These were decreased significantly (account for 42.9%) . Using color doppler we found that in 20 cases the blood flow of internal tumour were disappeared totally (71.4%), and in 8 cases were decreased (29.6%) . These rescults suggest that the color doppler play an important role in observing the primary focus secondary affection and vascularity of tumour when using carboplatin chemotherapy to treat the tumour by abdominal abministration.